A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name LMNA
Type somatic mutation
Species Homo sapiens
Tissue NA
Experiment Method other
Up/Down NA
Pro/Anti Pro
Funtion Description Hutchinson-Gilford progeria syndrome is a rare, sporadic, autosomal dominant syndrome that involves premature aging, generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. The genetic basis of most cases of thi
Regulation Gene NA
Year 2008
Pubmed ID 18256394
Title Phenotype and course of Hutchinson-Gilford progeria syndrome.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA