| Name |
LMNA
|
| Type |
somatic mutation
|
| Species |
Drosophila melanogaster
|
| Tissue |
NA
|
| Experiment Method |
RT-PCR,Western Blot,Immunocytochemistry,FISH
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Researchers link a novel mechanism for RNA export through nuclear envelope (NE) budding that requires A-type lamin, an inner nuclear membrane-associated protein, to accelerated aging observed in Drosophila LaminC (LamC) mutations. These LamC mutations wer
|
| Regulation Gene |
NA
|
| Year |
2016
|
| Pubmed ID |
27451905
|
| Title |
Lamin Mutations Accelerate Aging via Defective Export of Mitochondrial mRNAs through Nuclear Envelope Budding.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
1
|
| High-throughput |
NA
|