Details
| Name | LMNA |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | bone, muscle and skin |
| Experiment Method | RT-PCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | The Lmna mutation resulted in nuclear morphology defects and decreased lifespan of homozygous fibroblasts, suggesting premature cell death. |
| Regulation Gene | NA |
| Year | 2003 |
| Pubmed ID | 12748643 |
| Title | A progeroid syndrome in mice is caused by defects in A-type lamins. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |