Details
| Name | LMNA |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | cardiac |
| Experiment Method | PCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Mutations within the LMNA gene may therefore cause cardiomyopathy by disrupting the internal organization of the cardiomyocyte and/or altering the expression of transcription factors essential to normal cardiac development, aging or function. |
| Regulation Gene | NA |
| Year | 2005 |
| Pubmed ID | 15972724 |
| Title | Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |