Details
| Name | LRS-2 |
| Type | somatic mutation |
| Species | Caenorhabditis elegans |
| Tissue | NA |
| Experiment Method | PCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | A classical genetic screen identified a mutation in the mitochondrial leucyl-tRNA synthetase gene (lrs-2) that impaired mitochondrial function and was associated with longer-lifespan. |
| Regulation Gene | NA |
| Year | 2003 |
| Pubmed ID | 12447374 |
| Title | A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |