Details
| Name | M146V |
| Type | somatic mutation |
| Species | Rat Rattus |
| Tissue | hippocampal |
| Experiment Method | PCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | At 18 months, long-term potentiation in the CA1 was facilitated in the transgenic rats with a different pattern of synaptic enhancement. |
| Regulation Gene | PS1(presenillin-1) |
| Year | 2003 |
| Pubmed ID | 12742741 |
| Title | Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |