A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MDT-15
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans Strains
Experiment Method RNAi
Up/Down NA
Pro/Anti Anti
Funtion Description Mutation of mdt-15 increased the life span of FLA treated animals compared to wild-type animals with no difference observed between DR and ad libitum fed mdt-15 animals. We also examined mutants with altered insulin-IGF-1-like signaling (IIS), which is kn
Regulation Gene mdt-15
Year 2011
Pubmed ID 22132200
Title The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA