A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MTHFR
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description DNA from 361 subjects was screened for the thermolabile MTHFR variant with PCR. In the healthy younger subjects the mutant allele was 1.4 times more frequent compared to the older subjects (P = 0.01). This study shows no link between the mutation and the
Regulation Gene MTHFR
Year 1999
Pubmed ID 10583447
Title Methylenetetrahydrofolate reductase polymorphism, plasma homocysteine and age.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA