A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NA
Type somatic mutation
Species Caenorhabditis elegans
Tissue C. elegans samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description Through the use of RNAi and genetic mutants, we identify tatn-1, which is the worm ortholog of tyrosine aminotransferase and catalyzes the first step of the conserved tyrosine degradation pathway, as a novel regulator of the dauer decision and modulator o
Regulation Gene tatn-1
Year 2013
Pubmed ID 24385923
Title TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA