| Name |
NA
|
| Type |
somatic mutation
|
| Species |
Homo sapiens
|
| Tissue |
blood samples
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
We investigated whether this KCNQ1 missense mutation could form the genetic basis for AF and bradycardia simultaneously in this family. Sanger sequencing in a family with hereditary persistent AF identified a novel KCNQ1 variant (V241F) in a highly conser
|
| Regulation Gene |
KCNQ1
|
| Year |
2014
|
| Pubmed ID |
23989646
|
| Title |
A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation
|
| Drug |
NA
|
| Disease |
age-dependant bradycardia;persistent atrial fibrillation
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
somatic mutation
|
| High-throughput |
NA
|