Details
| Name | NA |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | WI-38 human diploid fibroblasts |
| Experiment Method | RNAi,qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Functional studies demonstrate that caveolin-1 acts as an endogenous inhibitor of Nrf2, as shown by the enhanced up-regulation of NQO1, an Nrf2 target gene, in caveolin-1-null MEFs and the activation or inhibition of a luciferase construct carrying an ant |
| Regulation Gene | Nrf2 |
| Year | 2013 |
| Pubmed ID | 23637463 |
| Title | Inhibition of nuclear factor-erythroid 2-related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |