Details
| Name | NA |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Our study is the first to describe a Cx43 mutation in which osteopenia is caused by increased rather than decreased osteoblast function and where activation of osteoclasts occurs not only through increased mbRANKL but an increase in a matrix protein that |
| Regulation Gene | Cx43 |
| Year | 2013 |
| Pubmed ID | 23606335 |
| Title | The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |