Details
| Name | NA |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | We report that two common variants of high-temperature requirement A1 (HTRA1) that increase the inherited risk of neovascular age-related macular degeneration (Nvage-related macular degeneration) harbor synonymous SNPs within exon 1 of HTRA1 that convert |
| Regulation Gene | HTRA1 |
| Year | 2013 |
| Pubmed ID | 23478260 |
| Title | Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1 |
| Drug | NA |
| Disease | age-related macular |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |