| Name |
CYR61
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
skin
|
| Experiment Method |
Western blots,qRT-PCR,ELISA,B-galactosidase measurement,Immunofluorescence staining
|
| Up/Down |
up
|
| Pro/Anti |
pro
|
| Funtion Description |
The anti-fibrotic effect of CYR61 was further demonstrated by delay in wound healing, inhibition of gel contraction, inactivation of the TGFB pathway, and early superoxide production associated with senescence in SSc fibroblasts.
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30884213
|
| Title |
Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma
|
| Drug |
NA
|
| Disease |
Scleroderma
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|