A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NA
Type somatic mutation
Species Homo sapiens
Tissue lung tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti NA
Funtion Description In multivariate analysis, we found a significant increase of EGFR mutation prevalence by increase of age (p-trend=0.0004).Consistent trend was observed among never-smoking females (p-trend=0.011) and never-smoking males also showed similar trend although
Regulation Gene EGFR
Year 2012
Pubmed ID 23036155
Title Impact of age on epidermal growth factor receptor mutation in lung cancer.
Drug NA
Disease lung cancer
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA