| Name |
NADH-dehydrogenase subunit 2
|
| Type |
somatic mutation
|
| Species |
Mouse
|
| Tissue |
Conplastic mice primary skin fibroblasts
|
| Experiment Method |
Western blot;Immunofluorescence staining;Quantitative real time PCR
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
Here we investigated a single nucleotide exchange (leucine to methionine) at position nt4738 in the mitochondrial NADH dehydrogenase subunit 2 (Nd2) gene of the respiratory chain. Primary fibroblasts derived from the conplastic mouse strain C57BL/6J-mtALR
|
| Regulation Gene |
NA
|
| Year |
2015
|
| Pubmed ID |
25839158
|
| Title |
A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
GSE63551
|