| Name |
P450
|
| Type |
somatic mutation
|
| Species |
Caenorhabditis elegans
|
| Tissue |
C. elegans strains
|
| Experiment Method |
Quantitative real-time PCR
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
The creation of a fat-5(tm420);cyp-35A2(gk317) mutant uncovered that the deletion of both genes resulted in a strain which is marked by an extended lifespan.Comprehensive transcriptomics revealed that several genes involved in aging and lipid transport/ho
|
| Regulation Gene |
NA
|
| Year |
2015
|
| Pubmed ID |
29124160
|
| Title |
The double mutation of cytochrome P450's and fatty acid desaturases affect lipid regulation and longevity in C. elegans.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|