A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type somatic mutation
Species Homo sapiens
Tissue colon
Experiment Method PCR
Up/Down differential expression
Pro/Anti NA
Funtion Description Significantly lower p53 mutation frequencies were observed among young (32 years old or younger) and old (86 years old or older) patient groups compared with an average age (39-85 years old) patient group
Regulation Gene p53
Year 2004
Pubmed ID 15449054
Title Influence of age on adenomatous polyposis coli and p53 mutation frequency in sporadic colorectal cancer-rarity of co-occurrence of mutations in APC, K-ras, and p53 genes.
Drug NA
Disease colorectal cancer
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA