Details
| Name | p53 |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | mouse embryonic fibroblasts |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Mutant (p53+/m) mice exhibit enhanced resistance to spontaneous tumours compared with wild-type (p53+/+) littermates. As p53+/m mice age, they display an early onset of phenotypes associated with ageing. These include reduced longevity, osteoporosis, gene |
| Regulation Gene | p53 |
| Year | 2002 |
| Pubmed ID | 11780111 |
| Title | p53 mutant mice that display early ageing-associated phenotypes |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |