A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p53
Type somatic mutation
Species Homo sapiens
Tissue NA
Experiment Method PCR
Up/Down NA
Pro/Anti Pro
Funtion Description both metabolic genes and p53 act on pathways related to cell ageing and death, and therefore certain composite genetic patterns could represent a generic mechanism of protection against ageing, not just against the development of chronic diseases.
Regulation Gene NA
Year 2003
Pubmed ID 15195682
Title Metabolic gene polymorphisms and p53 mutations in healthy centenarians and younger controls.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA