Details
| Name | pdk-1 |
| Type | somatic mutation |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | We show here that a loss-of-function mutation in pdk-1, the C. elegans homolog of the mammalian Akt/PKB kinase PDK1, results in constitutive arrest at the dauer stage and increased life span; these phenotypes are suppressed by a loss of function mutation |
| Regulation Gene | pdk-1 |
| Year | 1999 |
| Pubmed ID | 10364160 |
| Title | A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |