Details
| Name | Pit1 |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | We show here that mice homozygous for loss-of-function mutations at the Pit1 (Snell dwarf) locus show a >40% increase in mean and maximal longevity on the relatively long-lived (C3H/HeJ x DW/J)F(1) background. |
| Regulation Gene | Pit1 |
| Year | 2001 |
| Pubmed ID | 11371619 |
| Title | Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |