Details
| Name | PS |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | These data show a definite effect of the PS2 mutation on an age-dependent increase of Abeta42 content in the brain. |
| Regulation Gene | PS |
| Year | 1998 |
| Pubmed ID | 9648880 |
| Title | Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain. |
| Drug | NA |
| Disease | Alzheimer's disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |