A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type gene
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description The life-span extension caused by daf-2 mutations requires the activity of the gene daf-16. daf-16 appears to play a unique role in life-span regulation and encodes a member of the hepatocyte nuclear factor 3 (HNF-3)/forkhead family of transcriptional reg
Regulation Gene NA
Year 1997
Pubmed ID 9360933
Title daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA