A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PS1
Type somatic mutation
Species Mus musculus
Tissue NA
Experiment Method Western blot
Up/Down NA
Pro/Anti NA
Funtion Description In this paper we present results of mitochondrial protein changes in the brain of PS-1 transgenic mice as a function of age.However, in older mice combination of the PS-1 mutation and accumulated oxidative damage results in functional suppression of OXPHO
Regulation Gene PS-1
Year 2009
Pubmed ID 19241155
Title Quantitative Proteomic Analysis of Mitochondria in Aging PS-1 Transgenic Mice
Drug NA
Disease AD
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA