Details
| Name | PS1 |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | In APP/PS-1 mouse brain, there is a basal increase (at 1 month) in oxidative stress compared to the wild type (1 month), as measured by protein oxidation and lipid peroxidation. In addition, age-related elevation of oxidative damage was observed in APP/PS |
| Regulation Gene | PS-1 |
| Year | 2008 |
| Pubmed ID | 18762245 |
| Title | Oxidative damage in brain from human mutant APP/PS-2 double knock-in mice as a function of age |
| Drug | NA |
| Disease | NA |
| Environment Factors | Oxidation |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |