Details
| Name | R722W |
| Type | somatic mutation |
| Species | Mus musculus |
| Tissue | liver tissue |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | XpdTTD mice, harboring defects in nucleotide excision repair and transcription due to a mutation in the Xpd gene (R722W), display severe symptoms of premature aging but have a reduced incidence of cancer. |
| Regulation Gene | R722W |
| Year | 2008 |
| Pubmed ID | 18545656 |
| Title | Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |