A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description DAF-16is the soleorthologof theFOXOfamily of transcription factors in thenematodeCaenorhabditis elegans.It is responsible for activating genes involved inlongevity,lipogenesis,heat shocksurvival andoxidative stressresponses.It also protectsC.elegansduring
Regulation Gene NA
Year 2017
Pubmed ID 28954389
Title Diosgenin a phytosterol substitute for cholesterol, prolongs the lifespan and mitigates glucose toxicity via DAF-16/FOXO and GST-4 in Caenorhabditis elegans.
Drug NA
Disease NA
Environment Factors Diosgenin
Circulating NA
Variant NA
High-throughput NA