A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs11200638
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description At the same time, the common disease haplotype tagged by the in/del and rs11200638 has an effect on the transcriptional upregulation of the adjacent gene, HTRA1. These data implicate increased HTRA1 expression in the pathogenesis of AMD and highlight the
Regulation Gene HTRA1
Year 2010
Pubmed ID 20140183
Title Genetic and Functional Dissection of HTRA1 and LOC387716 in Age-Related Macular Degeneration
Drug NA
Disease AMD
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA