A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs2241394
Type somatic mutation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description We genotyped 13 tag single nucleotide polymorphisms (SNPs) that capture the majority of common variations in the C3 locus and tested for associations between these SNPs and wet age-related macular degeneration in a Japanese population comprising 420 case
Regulation Gene C3
Year 2011
Pubmed ID 22174912
Title A common complement C3 variant is associated with protection against wet age-related macular degeneration in a Japanese population
Drug NA
Disease age-related macular degeneration;polypoidal choroidal vasculopathy
Environment Factors NA
Circulating 1
Variant somatic mutation
High-throughput NA