A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SAGA
Type somatic mutation
Species Yeast
Tissue Yeast strains(Haploid strain C9,Industrial wine yeast L2056,The petite strains)
Experiment Method Western blotting
Up/Down NA
Pro/Anti Anti
Funtion Description Here we demonstrate that integrity of the SAGA complex is necessary for prolonged longevity, as its dismantling by SPT20 deletion causes a drop in CLS under both laboratory and winemaking conditions.The sch9 delta mutant is long-lived in synthetic SC med
Regulation Gene NA
Year 2015
Pubmed ID 25658705
Title Interplay among Gcn5, Sch9 and Mitochondria during Chronological Aging of Wine Yeast Is Dependent on Growth Conditions
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA