Details
| Name | sir4-42 |
| Type | somatic mutation |
| Species | Saccharomyces cerevisiae |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Our findings suggest that sir4-42 extends life span by preventing recruitment of the SIR proteins to HM loci and telomeres, thereby increasing their concentration at other chromosomal regions. |
| Regulation Gene | SIR4 |
| Year | 1995 |
| Pubmed ID | 7859289 |
| Title | Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |