A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SLC25A24
Type somatic mutation
Species Homo sapiens
Tissue bone
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description the SLC25A24 mutations lead to impaired mitochondrial ATP synthesis and cause hyperpolarization and increased proton leak in association with cell senescence.
Regulation Gene NA
Year 2018
Pubmed ID 29100094
Title De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA