A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOD2
Type somatic mutation
Species Fission yeast
Tissue parental strain ED0665;
Experiment Method MTT;RT-PCR;CLS
Up/Down Up
Pro/Anti Anti
Funtion Description SOD2 deficiency drastically decreased cell viability in the stationary phase. The mutation frequency of nuclear DNA in sod2 delta was elevated in the stationary phase, and cellular proteins and nuclear DNA were extensively degraded, concurrent with cell
Regulation Gene NA
Year 2016
Pubmed ID 26507459
Title Mitochondrial superoxide dismutase deficiency accelerates chronological aging in the fission yeast Schizosaccharomyces pombe.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA