A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SRS2
Type somatic mutation
Species Yeast
Tissue NA
Experiment Method PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Late-generation sgs1 and srs2 cells senesce due to apparent premature aging, most likely involving the accumulation of extrachromosomal rDNA circles.
Regulation Gene null
Year 2001
Pubmed ID 11290710
Title The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant somatic mutation
High-throughput NA