| Name |
SYCP2L
|
| Type |
somatic mutation
|
| Species |
Homo sapiens
|
| Tissue |
C57BL/6J mouse ovary and human ovary;293T cells and oocytes
|
| Experiment Method |
Western blot and immunofluorescence;RT-PCR
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
Female mice lacking SYCP2L undergo a significantly higher progressive loss of oocytes with age compared with wild-type females and are less fertile. Specifically, the pool of primordial oocytes becomes more rapidly depleted in SYCP2L-deficient than in wil
|
| Regulation Gene |
NA
|
| Year |
2015
|
| Pubmed ID |
26362258
|
| Title |
Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
NA
|
| High-throughput |
NA
|