Details
| Name | T414G |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | Skin and fibroblast samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | The T414G mutation is observed in human skin and is associated with photoaging.In addition, we have discovered frequent genetic linkage between a common photoaging-associated mtDNA deletion and the T414G mutation. This linkage indicates that mtDNA mutatio |
| Regulation Gene | mtDNA |
| Year | 2007 |
| Pubmed ID | 17578510 |
| Title | Ultraviolet radiation exposure accelerates the accumulation of the aging-dependent T414G mitochondrial DNA mutation in human skin. |
| Drug | NA |
| Disease | NA |
| Environment Factors | UV irradiation |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |