Details
| Name | TP53 |
| Type | somatic mutation |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | We showed that combination of TP53 variant genotypes and XRCC1 variant genotype is associated with the increased lung cancer risk in younger, but not elderly, smokers. In contrast, wild allele combination increases lung cancer risk for individuals over th |
| Regulation Gene | TP53 |
| Year | 2010 |
| Pubmed ID | 21403619 |
| Title | Age-related function of tumor suppressor gene TP53:contribution to cancer risk and progression |
| Drug | NA |
| Disease | lung cancer |
| Environment Factors | smoking |
| Circulating | 1 |
| Variant | somatic mutation |
| High-throughput | NA |