A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name AHR
Type TF
Species Homo sapiens
Tissue NHOK
Experiment Method qPCR,Western blot
Up/Down NA
Pro/Anti Pro
Funtion Description These results support the idea that progression of CSC-induced tumorigenesis may include an AHR-mediated inhibition of senescence that contributes to immortalization and agents that block the actions of the AHR may be effective components of novel cancer
Regulation Gene p15,INK4b,p16 INK4a
Year 2006
Pubmed ID 17070097
Title Cigarette smoke condensate and dioxin suppress culture shock induced senescence in normal human oral keratinocytes.
Drug NA
Disease NA
Environment Factors smoking
Circulating NA
Variant NA
High-throughput NA