A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name AP-1
Type TF
Species Homo sapiens
Tissue skin
Experiment Method other
Up/Down Up
Pro/Anti Pro
Funtion Description skin aging is associated with increased AP-1 activity, increased MMP expression, impaired TGF-_x0001_ signaling, enhanced collagen degradation, and decreased collagen synthesis
Regulation Gene c-Fos
Year 2002
Pubmed ID 12208239
Title UV-light-induced signal cascades and skin aging
Drug NA
Disease NA
Environment Factors UV irradiation
Circulating NA
Variant NA
High-throughput NA