Details
| Name | APA-1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | RT-PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Overexpression of APA-1 did not cause cell cycle arrest; but, it induced transcription of the extracellular matrix-remodeling genes MMP1 and PAI2, which are associated with fibroblast senescence. |
| Regulation Gene | MMP1,PAI2 |
| Year | 2002 |
| Pubmed ID | 12370286 |
| Title | Induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |