Details
| Name | EGR |
| Type | TF |
| Species | Mus musculus |
| Tissue | Mouse strains |
| Experiment Method | ChIP;EMSA;luciferase activity;Immunoblotting;Quantitative real-time PCR; |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Ectopic expression of Egr proteins induces growth arrest and senescence in H-RasV12-transformed NIH 3T3 cells in a manner that is partially dependent on C/EBPB.Indeed,each Egr protein efficiently restored C/EBPB levels. In addition, Egr expression inhibit |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 25535333 |
| Title | An Arf-Egr-C/EBPB pathway linked to ras-induced senescence and cancer. |
| Drug | NA |
| Disease | cancer |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |