Details
| Name | ATF4 |
| Type | TF |
| Species | Drosophila melanogaster |
| Tissue | Drosophila stocks |
| Experiment Method | Immunohistochemistry;Western blots;RT-PCR and quantitative real-time RT-PCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | GCN2 and its downstream transcription factor, ATF4, mediate 4E-BP induction, and GCN2 is required for lifespan extension in response to dietary restriction of amino acids. The 4E-BP intron contains ATF4-binding sites that not only respond to stress but al |
| Regulation Gene | 4E-BP |
| Year | 2017 |
| Pubmed ID | 27979906 |
| Title | 4E-BP is a target of the GCN2-ATF4 pathway during Drosophila development and aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |