Details
| Name | ATF6 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | mesenchymal stem cell (hMSC) |
| Experiment Method | PCR,other |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | CRISPR/Cas9-mediated inactivation of ATF6 in hMSCs, not in human embryonic stem cells and human adipocytes, results in premature cellular aging, characteristic of loss of endomembrane homeostasis. Transcriptomic analyses uncover cell type-specific constit |
| Regulation Gene | FOS |
| Year | 2018 |
| Pubmed ID | 29423270 |
| Title | ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |