A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Bach1
Type TF
Species Mus musculus
Tissue mouse embryonic fibroblasts
Experiment Method RNAi,qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description pRb became hypophosphorylated more rapidly in Bach1-deficient MEFs than in wild-type cells, suggesting that pRb activation was involved in their senescence. Bach1-deficient MEFs bypassed the senescence state when the expression of a subset of p53 target g
Regulation Gene NA
Year 2011
Pubmed ID 21110788
Title Identification of senescence-associated genes and their networks under oxidative stress by the analysis of Bach1
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA