A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BCL11B
Type TF
Species Mus musculus
Tissue mice samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description Analysis of auditory brainstem responses revealed age-related hearing loss in Bcl11b (+/-) heterozygous, but not wild-type, mice, which was evident as early as 3 months after birth. Histological abnormalities were observed in the outer hair cells of the B
Regulation Gene NA
Year 2011
Pubmed ID 21791875
Title Bcl11b heterozygosity leads to age-related hearing loss and degeneration of outer hair cells of the mouse cochlea
Drug NA
Disease age-related hearing loss
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA