Details
| Name | C/EBPB |
| Type | TF |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Upregulation of IL6 by C/EBPbeta has been shown to be necessary for oncogene-induced senescence, but the specific isoform of C/EBPbeta has not been investigated. We show that the C/EBPbeta1 isoform upregulates IL6 when introduced into normal fibroblasts. |
| Regulation Gene | NA |
| Year | 2010 |
| Pubmed ID | 20818427 |
| Title | Regulation of C/EBPbeta1 by Ras in mammary epithelial cells and the role of C/EBPbeta1 in oncogene-induced senescence |
| Drug | NA |
| Disease | breast cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |