| Name |
CCM3
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
HCAEC cells, hTERT-RPE1, and IMR90 cells
|
| Experiment Method |
Quantitative RT-PCR;Western blot;Immunofluorescence
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
We report in this study that lack of CCM3 unexpectedly impairs the senescence response of cells, and this is related to the inability of CCM3-deficient cells to induce the C/EBPB transcription factor and implement the senescence-associated secretory pheno
|
| Regulation Gene |
NA
|
| Year |
2015
|
| Pubmed ID |
25655101
|
| Title |
The cerebral cavernous malformation 3 gene is necessary for senescence induction.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
GSE54095
|