A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name c-fos
Type TF
Species Rabbits
Tissue vascular smooth muscle cell
Experiment Method Cell proliferation assay
Up/Down Up
Pro/Anti Pro
Funtion Description These studies suggest that age-associated increase in c-fos activity contributes to augmented cyclin A expression and VSMC proliferation in old animals
Regulation Gene c-fos
Year 2000
Pubmed ID 10728429
Title Age-dependent increase in c-fos activity and cyclin A expression in vascular smooth muscle cells. A potential link between aging, smooth muscle cell proliferation and atherosclerosis.
Drug NA
Disease atherosclerosis
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA