A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CHOP
Type TF
Species Mus musculus
Tissue pancreatic tissues
Experiment Method Western Blotting
Up/Down Up
Pro/Anti Pro
Funtion Description We examined several tissues in mice for induction of the unfolded protein response (UPR) following acute SD. In young animals, we found a robust induction of BiP in the pancreas, indicating an active UPR. At baseline, pancreata from aged animals exhibited
Regulation Gene NA
Year 2014
Pubmed ID 24102714
Title Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA